Il19^tm1Dnax
Targeted Allele Detail

Summary

• Symbol: Il19^tm1Dnax
• Name: interleukin 19; targeted mutation 1, DNAX Research Institute of Cellular and Molecular Biology
• MGI ID: MGI:3757697
• Synonyms: IL-19^-, IL19tm1Dnax
• Gene: Il19 Location: Chr1:130860393-130867852 bp, - strand Genetic Position: Chr1, 56.89 cM
• Alliance: Il19^tm1Dnax page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:124591
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exons 3 and 4 were replaced with a loxP-flanked neo cassette. (J:124591)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il19 Mutation: 21 strains or lines available

References

• Original: J:124591 Chan JR, et al., IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis. J Exp Med. 2006 Nov 27;203(12):2577-87
• All: 2 reference(s)