Dbx1^tm2(cre)Apie
Targeted Allele Detail

Summary

• Symbol: Dbx1^tm2(cre)Apie
• Name: developing brain homeobox 1; targeted mutation 2, Alessandra Pierani
• MGI ID: MGI:3757955
• Synonyms: Dbx1^Cre, Dbx1^IRES-Cre
• Gene: Dbx1 Location: Chr7:49281247-49286583 bp, - strand Genetic Position: Chr7, 31.44 cM
• Alliance: Dbx1^tm2(cre)Apie page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101434
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Dbx1^tm2(cre)Apie expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Dbx1 (MGI:94867)

• Mutation details: A hygro selection cassette containing an IRES domain and a Cre-recombinase gene were inserted into the downstream untranslated portion of the gene. (J:101434)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Dbx1 (mouse) Summary of all recombinase alleles driven by Dbx1. Alliance mouse Dbx1 gene page

Expression

In Mice Carrying this Mutation:

9 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Dbx1 Mutation: 25 strains or lines available

References

• Original: J:101434 Bielle F, et al., Multiple origins of Cajal-Retzius cells at the borders of the developing pallium. Nat Neurosci. 2005 Aug;8(8):1002-12
• All: 43 reference(s)