Tg(SV40-NRAS*G12D)1Sco
Transgene Detail

Summary

• Symbol: Tg(SV40-NRAS*G12D)1Sco
• Name: transgene insertion 1, Suzanne Cory
• MGI ID: MGI:3757990
• Synonyms: Emu-N-ras
• Transgene: Tg(SV40-NRAS*G12D)1Sco Location: unknown
• Alliance: Tg(SV40-NRAS*G12D)1Sco page

Transgene origin

• Strain of Origin: (C57BL/6 x SJL)F1

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The SV40 early region promoter with the immunoglobulin heavy chain enhancer (Emu) was fused to a human NRAS open reading frame carrying a G12D point mutation. (J:125150)

Tumor Data

List all tumor models in MMHCdb carrying Tg(SV40-NRAS*G12D)1Sco

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:125150 Harris AW, et al., Transgenic mouse models for hematopoietic tumorigenesis. Curr Top Microbiol Immunol. 1988;141:82-93
• All: 3 reference(s)