Taf4^tm1Idvd
Targeted Allele Detail

Summary

• Symbol: Taf4^tm1Idvd
• Name: TATA-box binding protein associated factor 4; targeted mutation 1, Irwin Davidson
• MGI ID: MGI:3758058
• Gene: Taf4 Location: Chr2:179553945-179618439 bp, - strand Genetic Position: Chr2, 102.42 cM, cytoband H4
• Alliance: Taf4^tm1Idvd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:125257
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A single loxP site was inserted upstream of exon 11 and a floxed hygromycin resistance cassette was inserted in intron 12. (J:125257)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Taf4 Mutation: 42 strains or lines available

References

• Original: J:125257 Mengus G, et al., TAF4 inactivation in embryonic fibroblasts activates TGF beta signalling and autocrine growth. EMBO J. 2005 Aug 3;24(15):2753-67
• All: 4 reference(s)