Aebp1^tm1Hsro
Targeted Allele Detail

Summary

• Symbol: Aebp1^tm1Hsro
• Name: AE binding protein 1; targeted mutation 1, Hyo-Sung Ro
• MGI ID: MGI:3758183
• Synonyms: AEBP1^-
• Gene: Aebp1 Location: Chr11:5811947-5822088 bp, + strand Genetic Position: Chr11, 3.88 cM
• Alliance: Aebp1^tm1Hsro page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:125333
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Sequence contained within intron 6 through intron 12 was replaced with a neo cassette. Lack of protein expression was confirmed by western blot of heart tissue with a poluyclonal Aebp1 antibody. (J:125333)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Aebp1 Mutation: 34 strains or lines available

References

• Original: J:125333 Ro HS, et al., Adipocyte enhancer-binding protein 1 modulates adiposity and energy homeostasis. Obesity (Silver Spring). 2007 Feb;15(2):288-302
• All: 3 reference(s)