Tg(Fabp4-Aebp1)1Hsro
Transgene Detail

Summary

• Symbol: Tg(Fabp4-Aebp1)1Hsro
• Name: transgene insertion 1, Hyo-Sung Ro
• MGI ID: MGI:3758185
• Transgene: Tg(Fabp4-Aebp1)1Hsro Location: unknown
• Alliance: Tg(Fabp4-Aebp1)1Hsro page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Fabp4-Aebp1)1Hsro expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Aebp1 (MGI:1197012)

• Mutation details: A 5.4kb DNA fragment containing the fat-specific promoter/enhancer from Fabp4 is used to drive the expression of Aebp1 in adipocytes and macrophages. Expression of Aebp1 is 4.5-fold higher in white adipose tissue in one transgenic line relative to in wild type mice. (J:125334)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:125334 Zhang L, et al., The role of AEBP1 in sex-specific diet-induced obesity. Mol Med. 2005 Jan-Dec;11(1-12):39-47
• All: 3 reference(s)