Pgm3^{Gt(W037B08)Wrst}
Gene trapped Allele Detail

Summary

• Symbol: Pgm3^{Gt(W037B08)Wrst}
• Name: phosphoglucomutase 3; gene trap W037B08, Wolfgang Wurst
• MGI ID: MGI:3758644
• Synonyms: Pgm3^gt
• Gene: Pgm3 Location: Chr9:86436430-86453895 bp, - strand Genetic Position: Chr9, 46.58 cM, cytoband E3.2
• Alliance: Pgm3^{Gt(W037B08)Wrst} page

Mutation origin

• Mutant Cell Line: W037B08
• Germline Transmission: Earliest citation of germline transmission: J:125094
• Parent Cell Line: TBV2 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pT1betageo
• Mutation details: The gene trap vector pT1betageo was inserted into intron 4, 87 bp downstream of exon 4. While a transcript is detectable by RT-PCR the resulting protein has less than 1% of wild-type enzymatic activity in the testes, spleen, pancreas and heart. (J:125094)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  W037B08	CL211001 ; (MGI Seq Detail)	5' RACE	Chr9:86449562-86452411 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  5 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pgm3 Mutation: 38 strains or lines available

References

• Original: J:125094 Greig KT, et al., Agm1/Pgm3-mediated sugar nucleotide synthesis is essential for hematopoiesis and development. Mol Cell Biol. 2007 Aug;27(16):5849-59
• All: 2 reference(s)