Bambi^tm1.1Jian
Targeted Allele Detail

Summary

• Symbol: Bambi^tm1.1Jian
• Name: BMP and activin membrane-bound inhibitor; targeted mutation 1.1, Rulang Jiang
• MGI ID: MGI:3758817
• Synonyms: Bambi^del
• Gene: Bambi Location: Chr18:3507923-3516404 bp, + strand Genetic Position: Chr18, 2.3 cM, cytoband A1
• Alliance: Bambi^tm1.1Jian page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:125093
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exon 1 containing the ATG was removed by cre-mediated recombination to create a null allele. RT-PCR confirmed the absence of a transcript from the allele. (J:125093)

Expression

In Mice Carrying this Mutation:	2 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bambi Mutation: 12 strains or lines available

References

• Original: J:125093 Chen J, et al., The TGF-beta pseudoreceptor gene Bambi is dispensable for mouse embryonic development and postnatal survival. Genesis. 2007 Aug;45(8):482-6
• All: 5 reference(s)