Sema3b^tm1Mom
Targeted Allele Detail

Summary

• Symbol: Sema3b^tm1Mom
• Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B; targeted mutation 1, Peter Mombearts
• MGI ID: MGI:3758884
• Synonyms: deltaB
• Gene: Sema3b Location: Chr9:107474873-107486428 bp, - strand Genetic Position: Chr9, 58.31 cM
• Alliance: Sema3b^tm1Mom page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:125485
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: All of the open reading frame, exons 1-17, were replaced with the ACNF cassette, which self-excised upon germline transmission leaving a null allele. (J:125485)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Sema3b Mutation: 31 strains or lines available

References

• Original: J:125485 Walz A, et al., Axonal wiring of guanylate cyclase-D-expressing olfactory neurons is dependent on neuropilin 2 and semaphorin 3F. Development. 2007;134:4063-72
• All: 2 reference(s)