Slc26a8^tm1Ggac
Targeted Allele Detail

Summary

• Symbol: Slc26a8^tm1Ggac
• Name: solute carrier family 26, member 8; targeted mutation 1, Gereard Gacon
• MGI ID: MGI:3759094
• Synonyms: Tat1^-
• Gene: Slc26a8 Location: Chr17:28856757-28909207 bp, - strand Genetic Position: Chr17, 14.82 cM
• Alliance: Slc26a8^tm1Ggac page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:125103
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEvBrd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 2 was replaced by an IRES-lacZ cassette followed by a neo cassette. PCR on genomic DNA was performed to confirm insertion. (J:125103)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc26a8 Mutation: 38 strains or lines available

References

• Original: J:125103 Toure A, et al., The testis anion transporter 1 (Slc26a8) is required for sperm terminal differentiation and male fertility in the mouse. Hum Mol Genet. 2007 Aug 1;16(15):1783-93
• All: 2 reference(s)