Zfp704^tm1Glh
Targeted Allele Detail

Summary

• Symbol: Zfp704^tm1Glh
• Name: zinc finger protein 704; targeted mutation 1, David J Goldhamer
• MGI ID: MGI:3759307
• Synonyms: Gig1^nlacZ
• Gene: Zfp704 Location: Chr3:9492080-9675145 bp, - strand Genetic Position: Chr3, 2.31 cM
• Alliance: Zfp704^tm1Glh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:125184
• Parent Cell Line: D1 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6J)F1

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A lacZ-3pA with a nuclear localization signal and a floxed PGKneo cassette were inserted into exon 1 to create a null allele. Removal of the cre cassette was achieve via a cross to mice carrying the Hprt1^tm1(cre)Mnn allele. Absence of transcript was confirmed by RT-PCR on homozygous mice. LacZ expression was confirmed by X-gal staining. (J:125184)

Expression

In Mice Carrying this Mutation:

82 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zfp704 Mutation: 39 strains or lines available

References

• Original: J:125184 Yamamoto M, et al., Cloning and characterization of a novel MyoD enhancer-binding factor. Mech Dev. 2007 Sep-Oct;124(9-10):715-28
• All: 1 reference(s)