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Tg(Spry2)69Tpo
Transgene Detail
Summary
Symbol: Tg(Spry2)69Tpo
Name: transgene insertion 69, Timothy P O'Brien
MGI ID: MGI:3759545
Synonyms: Spry2-BAC-69, Spry2-Tg-69
Transgene: Tg(Spry2)69Tpo  Location: unknown  
Alliance: Tg(Spry2)69Tpo page
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Spry2)69Tpo expresses 1 gene
 
Mutation detailsAn 80kb BAC encoding the Spry2 locus was isolated from a CITB-CJ7 (129S1/Sv) BAC library and used for pronuclear injection into C57BL/6J oocytes. Southern blot analysis determined a copy number of 1-2 for line 69. RT-PCR analysis of E14.5 embryonic palate tissue showed that line 69 expressed the transgenic Spry2 at ~25% of wild-type levels. (J:125229)
Phenotypes
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:125229 Welsh IC, et al., A dosage-dependent role for Spry2 in growth and patterning during palate development. Mech Dev. 2007 Sep-Oct;124(9-10):746-61
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory