Mapk1^tm1.1Kuta
Targeted Allele Detail

Summary

• Symbol: Mapk1^tm1.1Kuta
• Name: mitogen-activated protein kinase 1; targeted mutation 1.1, Kunio Takishima
• MGI ID: MGI:3759775
• Synonyms: Erk2^-
• Gene: Mapk1 Location: Chr16:16801246-16865317 bp, + strand Genetic Position: Chr16, 10.53 cM
• Alliance: Mapk1^tm1.1Kuta page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:125594
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exons 2 and 3 were removed by cre-mediated recombination following a cross to Tg(EIIa-cre)C5379Lmgd mice. (J:125594)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mapk1 Mutation: 43 strains or lines available

References

• Original: J:125594 Satoh Y, et al., Extracellular signal-regulated kinase 2 (ERK2) knockdown mice show deficits in long-term memory; ERK2 has a specific function in learning and memory. J Neurosci. 2007 Oct 3;27(40):10765-76
• All: 4 reference(s)