Tapt1^L5Jcs1
Chemically induced Allele Detail

Summary

• Symbol: Tapt1^L5Jcs1
• Name: transmembrane anterior posterior transformation 1; lethal 5 John C Schimenti 1
• MGI ID: MGI:3760260
• Synonyms: L5Jcs1
• Gene: Tapt1 Location: Chr5:44332496-44383968 bp, - strand Genetic Position: Chr5, 24.24 cM
• Alliance: Tapt1^L5Jcs1 page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: A T to A transition in the 5' splice site of intron 7 was induced by ENU mutagenesis. This mutation results in the skipping of exon 7 during splicing and a frame shift that causes the introduction of 12 anomalous amino acids after N279 and a premature stop. (J:125425)

Expression

In Mice Carrying this Mutation:	4 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tapt1 Mutation: 22 strains or lines available

References

• Original: J:100332 Wilson L, et al., Random mutagenesis of proximal mouse chromosome 5 uncovers predominantly embryonic lethal mutations. Genome Res. 2005 Aug;15(8):1095-105
• All: 3 reference(s)