Mycbp2^tm1.1Adia
Targeted Allele Detail

Summary

• Symbol: Mycbp2^tm1.1Adia
• Name: MYC binding protein 2, E3 ubiquitin protein ligase; targeted mutation 1.1, Aaron DiAntonio
• MGI ID: MGI:3760640
• Synonyms: Phr1^delta8,9
• Gene: Mycbp2 Location: Chr14:103350847-103584250 bp, - strand Genetic Position: Chr14, 51.79 cM
• Alliance: Mycbp2^tm1.1Adia page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:125702
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exons 8 and 9 were removed by cre-mediated recombination following a cross with Tg(ACTB-cre)2Mrt mice. RT-PCR was performed to confirm the removal of the exons. (J:125702)

Expression

In Structures Affected by this Mutation:

15 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mycbp2 Mutation: 224 strains or lines available

References

• Original: J:125702 Bloom AJ, et al., The requirement for Phr1 in CNS axon tract formation reveals the corticostriatal boundary as a choice point for cortical axons. Genes Dev. 2007 Oct 15;21(20):2593-606
• All: 2 reference(s)