Siah1btm1Ddlb
Targeted Allele Detail
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| Symbol: |
Siah1btm1Ddlb |
| Name: |
siah E3 ubiquitin protein ligase 1B; targeted mutation 1, Daivd D L Bowtell |
| MGI ID: |
MGI:3761096 |
| Synonyms: |
Siah1b- |
| Gene: |
Siah1b Location: ChrX:162853701-162859489 bp, - strand Genetic Position: ChrX, 76.11 cM
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| Alliance: |
Siah1btm1Ddlb page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:126183
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
Not Specified
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Exon 4 was replaced with a neo cassette. Western blot analysis of protein extracts from mouse embryonic fibroblast cells confirmed the expression of protein was reduced by half the level observed in wild-type cells.
(J:126183)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Siah1b Mutation: |
15 strains or lines available
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| Original: |
J:126183 Frew IJ, et al., Normal p53 function in primary cells deficient for Siah genes. Mol Cell Biol. 2002 Dec;22(23):8155-64 |
| All: |
1 reference(s) |
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Analysis Tools
