Tg(Emx1-cre/ERT2)1Kess
Transgene Detail

Summary

• Symbol: Tg(Emx1-cre/ERT2)1Kess
• Name: transgene insertion 1, Nicoletta Kessaris
• MGI ID: MGI:3761168
• Synonyms: Emx1-CreER^T2, Tg(Emx1-cre/ESR1)1Wdr
• Transgene: Tg(Emx1-cre/ERT2)1Kess Location: unknown
• Alliance: Tg(Emx1-cre/ERT2)1Kess page

Transgene origin

• Strain of Origin: (C57BL/6 x CBA)F1

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Emx1-cre/ERT2)1Kess expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Emx1

• Mutation details: A P1 artificial chromosome was created that contained a tamoxifen-inducible Cre recombinase with a nuclear localization signal fused to the initiation codon. Expression recapitulates endogenous expression in the cortical precursors. (J:105334)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Emx1 (species not specified) Summary of all recombinase alleles driven by Emx1. Comparative matrix view of recombinase activities

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:105334 Kessaris N, et al., Competing waves of oligodendrocytes in the forebrain and postnatal elimination of an embryonic lineage. Nat Neurosci. 2006 Feb;9(2):173-9
• All: 23 reference(s)