Endog^tm1Vdaw
Targeted Allele Detail

Summary

• Symbol: Endog^tm1Vdaw
• Name: endonuclease G; targeted mutation 1, Valina Dawson
• MGI ID: MGI:3761639
• Gene: Endog Location: Chr2:30061525-30064057 bp, + strand Genetic Position: Chr2, 21.29 cM, cytoband B
• Alliance: Endog^tm1Vdaw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:126132
• Parent Cell Line: MC1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2 and 3 were replaced with a PGK-neo cassette. The absence of protein product was confirmed by a western blot using protein extracts from the brain. (J:126132)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Endog Mutation: 12 strains or lines available

References

• Original: J:126132 David KK, et al., EndoG is dispensable in embryogenesis and apoptosis. Cell Death Differ. 2006 Jul;13(7):1147-55
• All: 1 reference(s)