Tg(Drd1a-cre)AGsc
Transgene Detail

Summary

• Symbol: Tg(Drd1a-cre)AGsc
• Name: transgene insertion A, Gunther Schutz
• MGI ID: MGI:3761818
• Synonyms: D1Cre, dr-1 Cre, Tg(Drd1a-cre)2Gsc
• Transgene: Tg(Drd1a-cre)AGsc Location: unknown
• Alliance: Tg(Drd1a-cre)AGsc page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Drd1a-cre)AGsc expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Drd1 (MGI:99578)

• Mutation details: A YAC containing the cre open reading frame with a nuclear localization signal and under the control of a Drd1a promoter was used to create a transgene. Expression was confirmed through crosses with three reporter lines and localized to the major dopaminoceptive regions. Line A contains 3 copies of the transgene. (J:126425)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Drd1 (mouse) Summary of all recombinase alleles driven by Drd1. Comparative matrix view of recombinase activities Alliance mouse Drd1 gene page

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available

Notes

% transgenic mouse lines were create (A, R, S, T and U). Lines T and U do not contain complete transgenes while the other three lines exhibit virtually identical expression patterns. Line A was choosen as the representative line.

References

• Original: J:126425 Lemberger T, et al., Expression of Cre recombinase in dopaminoceptive neurons. BMC Neurosci. 2007;8:4
• All: 38 reference(s)