Tg(Mylpf-cre)3Kraj
Transgene Detail

Summary

• Symbol: Tg(Mylpf-cre)3Kraj
• Name: transgene insertion 3, Stan Krajewski
• MGI ID: MGI:3761931
• Synonyms: CRE3, MLC2v-CRE3, MLCcre
• Transgene: Tg(Mylpf-cre)3Kraj Location: unknown
• Alliance: Tg(Mylpf-cre)3Kraj page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Mylpf-cre)3Kraj expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  rat

  Myl11 (24584)

  Mylpf

  (MGI:97273)

• Mutation details: A 250-bp fragment of the rat ventricular light chain II gene (Mylpf) was used as promoter to drive expression of the cre recombinase cDNA. Crosses of these mice were made to mice (dh4) carrying a transgenic reporter gene (a dominant-hyg^R gene separated from a constitutive PGK promoter by a loxP-flanked PGK-neo cassette; cre recombination results in generation of the active-hyg^R allele detected by PCR). Line 3 was determined to express cre selectively in the brain. (J:99342)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Myl11 (rat) Summary of all recombinase alleles driven by Myl11. Comparative matrix view of recombinase activities Alliance rat Myl11 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:99342 Banares S, et al., Novel pan-neuronal Cre-transgenic line for conditional ablation of genes in the nervous system. Genesis. 2005 May;42(1):6-16
• All: 6 reference(s)