Il36rn^tm1Hblu
Targeted Allele Detail

Summary

• Symbol: Il36rn^tm1Hblu
• Name: interleukin 36 receptor antagonist; targeted mutation 1, Hal Blumberg
• MGI ID: MGI:3762028
• Synonyms: IL1F5^-, IL-36Ra^-
• Gene: Il36rn Location: Chr2:24166966-24172444 bp, + strand Genetic Position: Chr2, 16.31 cM
• Alliance: Il36rn^tm1Hblu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:126327
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 1 through 3 were replaced with a lacZ-neo cassette. Insertion was confirmed by Sourthen blot analysis. (J:126327)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il36rn Mutation: 22 strains or lines available

References

• Original: J:126327 Blumberg H, et al., Opposing activities of two novel members of the IL-1 ligand family regulate skin inflammation. J Exp Med. 2007 Oct 29;204(11):2603-14
• All: 5 reference(s)