Tg(CD207-Dta)312Dhka
Transgene Detail

Summary

• Symbol: Tg(CD207-Dta)312Dhka
• Name: transgene insertion 312, Daniel H Kaplan
• MGI ID: MGI:3762048
• Synonyms: Langerin-DTA, Tg(CD207-Dta)1Dhka
• Transgene: Tg(CD207-Dta)312Dhka Location: unknown
• Alliance: Tg(CD207-Dta)312Dhka page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: A transgene was created by inserting IRES sequences and the diphtheria toxin subunit A coding region into the 3' UTR of human the CD207 gene. Insertion was confirmed by PCR on genomic DNA. (J:113309)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:113309 Kaplan DH, et al., Epidermal langerhans cell-deficient mice develop enhanced contact hypersensitivity. Immunity. 2005 Dec;23(6):611-20
• All: 37 reference(s)