Cideb^tm1Pli
Targeted Allele Detail

Summary

• Symbol: Cideb^tm1Pli
• Name: cell death-inducing DNA fragmentation factor, alpha subunit-like effector B; targeted mutation 1, Peng Li
• MGI ID: MGI:3762191
• Gene: Cideb Location: Chr14:55991509-55995881 bp, - strand Genetic Position: Chr14, 28.19 cM, cytoband C1
• Alliance: Cideb^tm1Pli page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:126556
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The 3 C-terminal exons were replaced with a neo cassette. The absence of protein was confirmed by western blot analysis using proteins extracted from liver and kidney. (J:126556)

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cideb Mutation: 19 strains or lines available

References

• Original: J:126556 Li JZ, et al., Cideb regulates diet-induced obesity, liver steatosis, and insulin sensitivity by controlling lipogenesis and fatty acid oxidation. Diabetes. 2007 Oct;56(10):2523-32
• All: 9 reference(s)