Tg(Mbp-cre)29Miur
Transgene Detail

Summary

• Symbol: Tg(Mbp-cre)29Miur
• Name: transgene insertion 29, Masayuki Miura
• MGI ID: MGI:3762376
• Synonyms: MBP-cre
• Transgene: Tg(Mbp-cre)29Miur Location: unknown
• Alliance: Tg(Mbp-cre)29Miur page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Mbp-cre)29Miur expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Mbp (MGI:96925)

• Mutation details: The transgene consists of 6.3 kb of the mouse Mbp promoter, a nuclear localization signal, a cre recombinase gene and a polyadenylation signal. The construct was microinjected into fertilized C57BL/6 eggs. Mice of line 29 were shown to only express cre in the oligodendrocytes in the brain, and testis also, using RT-PCR. (J:126593)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Mbp (mouse) Summary of all recombinase alleles driven by Mbp. Comparative matrix view of recombinase activities Alliance mouse Mbp gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:126593 Hisahara S, et al., Targeted expression of baculovirus p35 caspase inhibitor in oligodendrocytes protects mice against autoimmune-mediated demyelination. EMBO J. 2000 Feb 1;19(3):341-8
• All: 3 reference(s)