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Tg(CAG-p35)1Miur
Transgene Detail
Summary
Symbol: Tg(CAG-p35)1Miur
Name: transgene insertion 1, Masayuki Miura
MGI ID: MGI:3762384
Synonyms: p35, Tg(ACTB-p35)1Miur, Tg(CAG-p35)1Miur
Transgene: Tg(CAG-p35)1Miur  Location: unknown  
Alliance: Tg(CAG-p35)1Miur page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThe transgene carries a floxed neo sequence, the baculovirus p35 coding sequence and a polyadenylation signal downstream of a chicken beta-actin promoter. Upon Cre-mediated excision of the loxP-neo-loxP sequence, the modified allele expresses p35 in tissues where Cre is expressed. (J:126593)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:126593 Hisahara S, et al., Targeted expression of baculovirus p35 caspase inhibitor in oligodendrocytes protects mice against autoimmune-mediated demyelination. EMBO J. 2000 Feb 1;19(3):341-8
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory