Tg(KRT14-rtTA)F42Efu
Transgene Detail

Summary

• Symbol: Tg(KRT14-rtTA)F42Efu
• Name: transgene insertion F42, Elaine Fuchs
• MGI ID: MGI:3762564
• Synonyms: K14-rtTA, K14rtTA
• Transgene: Tg(KRT14-rtTA)F42Efu Location: unknown
• Alliance: Tg(KRT14-rtTA)F42Efu page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Transactivator)
• Mutation: Insertion
• Mutation details: A transgenic vector incorporating the human keratin 14 promoter/enhancer, rabbit beta globin 5' untranslated region (UTR) for stabilization of transcript, the reverse tetracycline regulatable transactivator protein (rtTA2S-M2-VP16), and the keratin 14 3' UTR was injected into FVB embryos. (J:56822, J:116057)

Disease models

Tumor Data

List all tumor models in MMHCdb carrying Tg(KRT14-rtTA)F42Efu

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:116057 Nguyen H, et al., Tcf3 governs stem cell features and represses cell fate determination in skin. Cell. 2006 Oct 6;127(1):171-83
• All: 67 reference(s)