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Tg(tetO-Tcf3)1Efu
Transgene Detail
Summary
Symbol: Tg(tetO-Tcf3)1Efu
Name: transgene insertion 1, Elaine Fuchs
MGI ID: MGI:3762570
Synonyms: Tg(TRE-Tcf3)1Efu, TRE-mycTcf3
Transgene: Tg(tetO-Tcf3)1Efu  Location: unknown  
Alliance: Tg(tetO-Tcf3)1Efu page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Epitope tag, Inducible, Inserted expressed sequence)
Inducer:    doxycycline/tetracycline
Mutation:    Insertion
 
Mutation detailsMurine Tcf3 cDNA was tagged with an amino-terminal C-myc epitope to distinguish it from endogenous Tcf3. This tagged cDNA was placed under control of a tetracycline regulatory element (TRE) and a CMV minimal promoter. A rabbit beta globin intron was located between the TRE/CMV promoter sequences and the Tcf3 cDNA. The 3' beta-globin UTR was located downstream of the Tcf3 sequence. (J:116057)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:116057 Nguyen H, et al., Tcf3 governs stem cell features and represses cell fate determination in skin. Cell. 2006 Oct 6;127(1):171-83
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory