Crygd^L23
Chemically induced Allele Detail

Summary

• Symbol: Crygd^L23
• Name: crystallin, gamma D; L23
• MGI ID: MGI:3762620
• Synonyms: Crygd^m1Btlr, gamma D (V76)
• Gene: Crygd Location: Chr1:65101031-65102611 bp, - strand Genetic Position: Chr1, 32.8 cM
• Alliance: Crygd^L23 page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: A T-to-A transversion found within the gene is predicted to result in a substitution of valine at position 76 with an aspartate in the encoded protein. (J:126881)
• Inheritance: Dominant

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Crygd Mutation: 16 strains or lines available

References

• Original: J:126881 Wang K, et al., GammaD-crystallin associated protein aggregation and lens fiber cell denucleation. Invest Ophthalmol Vis Sci. 2007 Aug;48(8):3719-28
• All: 1 reference(s)