Tg(Ins2-cre)6Lt
Transgene Detail

Summary

• Symbol: Tg(Ins2-cre)6Lt
• Name: transgene insertion 6, Edward Leiter
• MGI ID: MGI:3762760
• Transgene: Tg(Ins2-cre)6Lt Location: unknown
• Alliance: Tg(Ins2-cre)6Lt page

Transgene origin

• Strain of Origin: NOD/ShiLt

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Ins2-cre)6Lt expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  rat

  Ins2 (24506)

  Ins2	(MGI:96573)

• Mutation details: A construct with the rat insulin II promoter driving the cre recombinase gene was injected directly into NOD/ShiLt embryos. (J:127015)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Ins2 (rat) Summary of all recombinase alleles driven by Ins2. Alliance rat Ins2 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:127015 Leiter EH, et al., Unexpected functional consequences of xenogeneic transgene expression in beta-cells of NOD mice. Diabetes Obes Metab. 2007 Nov;9 Suppl 2:14-22
• All: 2 reference(s)