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Tg(Prnp-PRNP)32Tkit
Transgene Detail
Summary
Symbol: Tg(Prnp-PRNP)32Tkit
Name: transgene insertion 32, Tetsuyuki Kitamoto
MGI ID: MGI:3762800
Synonyms: Tg-Bov#32
Transgene: Tg(Prnp-PRNP)32Tkit  Location: unknown  
Alliance: Tg(Prnp-PRNP)32Tkit page
Transgene
origin
Strain of Origin:  Not Applicable
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Prnp-PRNP)32Tkit expresses 1 gene
 
Mutation detailsThe transgene contains bovine PRNP under the control of the mouse promoter. Two copies of the transgene are present in line 32. (J:105882)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Notes
Transgenic mice do not produce PrPc in follicular dendritic cells.
References
Original:  J:105882 Asano M, et al., vCJD prion acquires altered virulence through trans-species infection. Biochem Biophys Res Commun. 2006 Mar 31;342(1):293-9
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory