Tg(Prnp-PRNP*)1Tkit
Transgene Detail

Summary

• Symbol: Tg(Prnp-PRNP*)1Tkit
• Name: transgene insertion 1, Tetsuyuki Kitamoto
• MGI ID: MGI:3762868
• Synonyms: Tg-Hu129M4R
• Transgene: Tg(Prnp-PRNP*)1Tkit Location: unknown
• Alliance: Tg(Prnp-PRNP*)1Tkit page

Transgene origin

• Strain of Origin: Not Applicable

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Prnp-PRNP*)1Tkit expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  PRNP (5621)

  Prnp	(MGI:97769)

• Mutation details: The transgene contains the human variant of PRNP with a methionine at amino acid position 129 and four octapeptid repeats under the control of the mouse promoter. (J:126777)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:126777 Kobayashi A, et al., Cross-sequence transmission of sporadic Creutzfeldt-Jakob disease creates a new prion strain. J Biol Chem. 2007 Oct 12;282(41):30022-8
• All: 1 reference(s)