Ptprv^tm1Kry
Targeted Allele Detail

Summary

• Symbol: Ptprv^tm1Kry
• Name: protein tyrosine phosphatase receptor type V; targeted mutation 1, Gerard Karsenty
• MGI ID: MGI:3762914
• Synonyms: Esp^flox
• Gene: Ptprv Location: Chr1:135036236-135060313 bp, - strand Genetic Position: Chr1, 58.24 cM, cytoband F-G
• Alliance: Ptprv^tm1Kry page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:126780
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: LoxP sites were inserted into introns 23 and 35 along with a floxed neo cassette downstream of exon 35. PCR genotyping was used to confirm the insertions. (J:126780)

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ptprv Mutation: 30 strains or lines available

References

• Original: J:126780 Lee NK, et al., Endocrine regulation of energy metabolism by the skeleton. Cell. 2007 Aug 10;130(3):456-69
• All: 2 reference(s)