Tg(Thy1-Syt1/ECFP)1Sud
Transgene Detail
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| Symbol: |
Tg(Thy1-Syt1/ECFP)1Sud |
| Name: |
transgene insertion 1, Thomas C Sudhof |
| MGI ID: |
MGI:3762948 |
| Synonyms: |
Syt1 transgenic, Tg(Thy1-Syt1-ECFP)1Sud, TMC |
| Transgene: |
Tg(Thy1-Syt1/ECFP)1Sud Location: unknown
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| Alliance: |
Tg(Thy1-Syt1/ECFP)1Sud page
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| Transgene Type: |
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Transgenic (Reporter) |
| Mutation: |
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Insertion
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Mutation details: A transgenic vector was designed to create a rat synaptotagmin 1/enhanced cyan fluorescent protein (ECFP) fusion protein under the control of a mouse Thy1 promoter lacking exon3 and the flanking introns (to make gene expression neuron-specific). Expression is detected only in the brain with fluorescence observed throughout the brain, marking synaptic vesicles.
(J:105052)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:105052 Han W, et al., C-terminal ECFP fusion impairs synaptotagmin 1 function: crowding out synaptotagmin 1. J Biol Chem. 2005 Feb 11;280(6):5089-100 |
| All: |
1 reference(s) |
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Analysis Tools
