Tg(Pdgfrb-cre)9Rha
Transgene Detail

Summary

• Symbol: Tg(Pdgfrb-cre)9Rha
• Name: transgene insertion 9, Ralf H Adams
• MGI ID: MGI:3763193
• Synonyms: Pdgfrb-Cre9
• Transgene: Tg(Pdgfrb-cre)9Rha Location: unknown
• Alliance: Tg(Pdgfrb-cre)9Rha page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Pdgfrb-cre)9Rha expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Pdgfrb (MGI:97531)

• Mutation details: A transgenic construct containing sequence encoding Cre recombinase under the control of the mouse platelet derived growth factor receptor, beta polypeptide promoter and a SV40 polyadenylation site sequence was injected into fertilized CBA x C57BL/6J mouse eggs. Founder line 9 was established. Cre recombinase expression is detected mural cells (vascular smooth muscle cells and pericytes) of the skin, intestine, kidney, lung, and the CNS vascular plexus as well as other organs. (J:115909)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Pdgfrb (mouse) Summary of all recombinase alleles driven by Pdgfrb. Alliance mouse Pdgfrb gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:115909 Foo SS, et al., Ephrin-B2 controls cell motility and adhesion during blood-vessel-wall assembly. Cell. 2006 Jan 13;124(1):161-73
• All: 11 reference(s)