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Tead4tm1Bnno
Targeted Allele Detail
Summary
Symbol: Tead4tm1Bnno
Name: TEA domain family member 4; targeted mutation 1, Andres Buonanno
MGI ID: MGI:3763361
Synonyms: Tead4lox
Gene: Tead4  Location: Chr6:128204106-128277776 bp, - strand  Genetic Position: Chr6, 62.92 cM
Alliance: Tead4tm1Bnno page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:126338
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA floxed neo cassette was inserted downstream of exon 2 and an additional loxP site was inserted upstream of exon 2. Insertion was confirmed by Southern blot analysis. (J:126338)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 10 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tead4 Mutation:  75 strains or lines available
References
Original:  J:126338 Yagi R, et al., Transcription factor TEAD4 specifies the trophectoderm lineage at the beginning of mammalian development. Development. 2007 Nov;134(21):3827-36
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory