Tead4^tm1Bnno
Targeted Allele Detail

Summary

• Symbol: Tead4^tm1Bnno
• Name: TEA domain family member 4; targeted mutation 1, Andres Buonanno
• MGI ID: MGI:3763361
• Synonyms: Tead4lox
• Gene: Tead4 Location: Chr6:128204106-128277776 bp, - strand Genetic Position: Chr6, 62.92 cM
• Alliance: Tead4^tm1Bnno page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:126338
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A floxed neo cassette was inserted downstream of exon 2 and an additional loxP site was inserted upstream of exon 2. Insertion was confirmed by Southern blot analysis. (J:126338)

Expression

In Mice Carrying this Mutation:

10 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tead4 Mutation: 75 strains or lines available

References

• Original: J:126338 Yagi R, et al., Transcription factor TEAD4 specifies the trophectoderm lineage at the beginning of mammalian development. Development. 2007 Nov;134(21):3827-36
• All: 7 reference(s)