Gabpa^tm1Agro
Targeted Allele Detail

Summary

• Symbol: Gabpa^tm1Agro
• Name: GA repeat binding protein, alpha; targeted mutation 1, Alan G Rosmarin
• MGI ID: MGI:3763374
• Synonyms: Gabpa^fl
• Gene: Gabpa Location: Chr16:84631813-84660667 bp, + strand Genetic Position: Chr16, 46.92 cM, cytoband C3-4
• Alliance: Gabpa^tm1Agro page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:126422
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A neo cassette with a 3' loxP site was inserted downstream of exon 9 and an additional loxP site was inserted between exon 7 and 8. Southern blot analysis PCR genotyping were used to confirm the insertion. (J:126422)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gabpa Mutation: 67 strains or lines available

References

• Original: J:126422 Yang ZF, et al., The Ets transcription factor GABP is required for cell-cycle progression. Nat Cell Biol. 2007 Mar;9(3):339-46
• All: 4 reference(s)