Ptpn4^tm1Tya
Targeted Allele Detail

Summary

• Symbol: Ptpn4^tm1Tya
• Name: protein tyrosine phosphatase, non-receptor type 4; targeted mutation 1, Tadashi Yamamoto
• MGI ID: MGI:3764684
• Synonyms: PTPMEG^-
• Gene: Ptpn4 Location: Chr1:119580197-119765281 bp, - strand Genetic Position: Chr1, 52.39 cM, cytoband E2
• Alliance: Ptpn4^tm1Tya page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:127245
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A Tau-LacZ cassette and a floxed PGK-neo cassette was inserted at the translation initiation codon. The absence of protein product was confirmed by western blot analysis on 8 week old cerebella. (J:127245)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ptpn4 Mutation: 50 strains or lines available

References

• Original: J:127245 Kina S, et al., Involvement of protein-tyrosine phosphatase PTPMEG in motor learning and cerebellar long-term depression. Eur J Neurosci. 2007 Oct;26(8):2269-78
• All: 2 reference(s)