Ripply2^tm1Asas
Targeted Allele Detail

Summary

• Symbol: Ripply2^tm1Asas
• Name: ripply transcriptional repressor 2; targeted mutation 1, Makoto Asashima
• MGI ID: MGI:3764703
• Gene: Ripply2 Location: Chr9:86897590-86901970 bp, + strand Genetic Position: Chr9, 46.69 cM
• Alliance: Ripply2^tm1Asas page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:122747
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The second exon was replaced with lacZ and a PGK-neo cassette. This resulted in lacZ following the first ATG of the gene. (J:122747)

Disease models

Expression

In Mice Carrying this Mutation:	7 assay results
In Structures Affected by this Mutation:	5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ripply2 Mutation: 15 strains or lines available

References

• Original: J:122747 Chan T, et al., Ripply2 is essential for precise somite formation during mouse early development. FEBS Lett. 2007 Jun 12;581(14):2691-6
• All: 1 reference(s)