Kiss1r^Gt1Stei
Gene trapped Allele Detail

Summary

• Symbol: Kiss1r^Gt1Stei
• Name: KISS1 receptor; gene trap 1, Robert A Steiner
• MGI ID: MGI:3764967
• Synonyms: GPR54^-, Kiss1r^m1Askn
• Gene: Kiss1r Location: Chr10:79752805-79758107 bp, + strand Genetic Position: Chr10, 39.72 cM
• Alliance: Kiss1r^Gt1Stei page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:127450
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Gene trapped (Null/knockout)
• Mutation: Insertion of gene trap vector
• Mutation details: A retroviral vector containing a selection marker, termination codons in all reading frames, a splice acceptor and a transcription terminator inserted into the locus. PCR confirmed recombination and ISH on brain tissue confirmed gene inactivation. (J:127450)

Expression

In Structures Affected by this Mutation:

9 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kiss1r Mutation: 21 strains or lines available

References

• Original: J:127450 Dungan HM, et al., The role of kisspeptin-GPR54 signaling in the tonic regulation and surge release of gonadotropin-releasing hormone/luteinizing hormone. J Neurosci. 2007 Oct 31;27(44):12088-95
• All: 9 reference(s)