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Evltm1Fbg
Targeted Allele Detail
Summary
Symbol: Evltm1Fbg
Name: Ena-vasodilator stimulated phosphoprotein; targeted mutation 1, Frank B Gertler
MGI ID: MGI:3764986
Synonyms: ee
Gene: Evl  Location: Chr12:108520979-108654775 bp, + strand  Genetic Position: Chr12, 59.46 cM, cytoband F2
Alliance: Evltm1Fbg page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:127447
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 2 and 3, encoding the EVH1 domain, were replaced with a neo cassette. The absence of protein product was confirmed by western blot analysis of protien extracted from adult brains. (J:127447)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 22 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Evl Mutation:  49 strains or lines available
References
Original:  J:127447 Kwiatkowski AV, et al., Ena/VASP Is Required for neuritogenesis in the developing cortex. Neuron. 2007 Nov 8;56(3):441-55
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory