Tg(Eno2-Ighmbp2)17Cx
Transgene Detail

Summary

• Symbol: Tg(Eno2-Ighmbp2)17Cx
• Name: transgene insertion 17, Gregory A Cox
• MGI ID: MGI:3765055
• Synonyms: TgNI
• Transgene: Tg(Eno2-Ighmbp2)17Cx Location: unknown
• Alliance: Tg(Eno2-Ighmbp2)17Cx page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Eno2-Ighmbp2)17Cx expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Ighmbp2 (MGI:99954)

• Tg(Eno2-Ighmbp2)17Cx expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  rat

  Eno2 (24334)

  Eno2	(MGI:95394)

• Mutation details: A 3.1 kb mouse Ighmbp2 cDNA sequence was placed under the control of a 4 kb sequence containing the rat Eno2 promoter. Transgene expression was limited to the central nervous system as confirmed by RT-PCR expression using primers within exon 1. (J:90418)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:90418 Maddatu TP, et al., Transgenic rescue of neurogenic atrophy in the nmd mouse reveals a role for Ighmbp2 in dilated cardiomyopathy. Hum Mol Genet. 2004 Jun 1;13(11):1105-15
• All: 2 reference(s)