Morc3^tm1Noin
Targeted Allele Detail

Summary

• Symbol: Morc3^tm1Noin
• Name: microrchidia 3; targeted mutation 1, Norimitsu Inoue
• MGI ID: MGI:3765156
• Gene: Morc3 Location: Chr16:93629009-93672961 bp, + strand Genetic Position: Chr16, 54.88 cM
• Alliance: Morc3^tm1Noin page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:127492
• Parent Cell Line: RW-4 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Part of exon 4 (112 bp) and exon 5 were replaced with hrGFP and a floxed neo cassette. The absence of protein protduct was confirmed by western blot analysis on mouse embryonic fibroblasts. (J:127492)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Morc3 Mutation: 80 strains or lines available

References

• Original: J:127492 Takahashi K, et al., Dynamic regulation of p53 subnuclear localization and senescence by MORC3. Mol Biol Cell. 2007 May;18(5):1701-9
• All: 1 reference(s)