Stx1a^tm1.1Sud
Targeted Allele Detail

Summary

• Symbol: Stx1a^tm1.1Sud
• Name: syntaxin 1A (brain); targeted mutation 1.1, Thomas C Sudhof
• MGI ID: MGI:3765939
• Synonyms: XRA
• Gene: Stx1a Location: Chr5:135052336-135079954 bp, + strand Genetic Position: Chr5, 74.95 cM
• Alliance: Stx1a^tm1.1Sud page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:144771
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A targeting vector was used to introduce a Flp-flanked neomycin resistance cassette to intron 1 and a loxP-flanked green fluorescent protein (GFP) segment to exon 2 of the gene. The GFP segment was deleted from targeted animals through crosses with a Cre strain. (J:144771)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Stx1a Mutation: 26 strains or lines available

References

• Original: J:144771 Sudhof TC, Generation of an Stx1a mutant allele. MGI Direct Data Submission. 2009
• All: 3 reference(s)