Immp2l^{Tg(Tyr)979Ove}
Transgenic Allele Detail

Summary

• Symbol: Immp2l^{Tg(Tyr)979Ove}
• Name: IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae); transgene insertion 979, Paul A Overbeek
• MGI ID: MGI:3765965
• Synonyms: Immp2lTg(Tyr)979OB
• Gene: Immp2l Location: Chr12:41074089-42002371 bp, + strand Genetic Position: Chr12, 18.69 cM, cytoband B3
• Alliance: Immp2l^{Tg(Tyr)979Ove} page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: A 5.5 kb fragment containing the LTR-Tyr expression cassette was injected into homozygous FVB/N fertilized eggs. A 50 kb deletion within the sixth intron was associated with the transgene insertion. A truncated mRNA containing just the first 6 exons was the only mRNA detected by RT-PCR. (J:128071)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Immp2l Mutation: 28 strains or lines available

References

• Original: J:128071 Lu B, et al., A mutation in the inner mitochondrial membrane peptidase 2-like gene (Immp2l) affects mitochondrial function and impairs fertility in mice. Biol Reprod. 2008 Apr;78(4):601-10
• All: 12 reference(s)