Tg(Thy1-EGFP)MJrs
Transgene Detail
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Symbol: |
Tg(Thy1-EGFP)MJrs |
Name: |
transgene insertion M, Joshua R Sanes |
MGI ID: |
MGI:3766828 |
Synonyms: |
GFP line-M, GFP-M, Thy1-GFP line M, Thy1-GFP/M, Thy1-GFPM, Thy1::GFP-M |
Transgene: |
Tg(Thy1-EGFP)MJrs Location: unknown
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Alliance: |
Tg(Thy1-EGFP)MJrs page
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Transgene Type: |
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Transgenic (Reporter) |
Mutation: |
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Insertion
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Mutation details: The Thy1-GFP transgene was designed with a modified regulatory region of the "murine thy1.2 gene" (extending from the promoter to the intron following exon 4, excluding exon 3 and its flanking introns) upstream of an enhanced green fluorescent protein (EGFP) sequence. Line M was subsequently established and analyzed. Expression of EGFP is detected primarily in mossy fibers in internal granule layer of the cerebellum (10-80% incidence). Less than 10% of all motor axons, retinal ganglion cells, lumbar dorsal root ganglion, and cortex express EGFP, with no reported expression in other tested neuronal tissues.
(J:93699)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Original: |
J:93699 Feng G, et al., Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP. Neuron. 2000 Oct;28(1):41-51 |
All: |
228 reference(s) |
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