Adamts20^bt-2H
Spontaneous Allele Detail

Summary

• Symbol: Adamts20^bt-2H
• Name: ADAM metallopeptidase with thrombospondin type 1 motif 20; belted 2 Harwell
• MGI ID: MGI:3766915
• Synonyms: Adamts20^bt-9J
• Gene: Adamts20 Location: Chr15:94166177-94329966 bp, - strand Genetic Position: Chr15, 48.2 cM
• Alliance: Adamts20^bt-2H page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: Complemetation testing demonstrated allelism between this mutation and Adamts20^bt-Bei1. Sequence analysis identified the molecular lesion as a a C-to-T transition at nucleotide position 2451 (NM_177431.5:c.2281C>T), which is predicted to replace a highly-conserved leucine in the protein's spacer domain with phenylalanine (L761F). (J:133403)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Adamts20 Mutation: 93 strains or lines available

References

• Original: J:106083 Lamoreux ML, Strain-specific white-spotting patterns in laboratory mice. Pigment Cell Res. 1999 Dec;12(6):383-90
• All: 2 reference(s)