Tg(Ascl1-EGFP,-cre)1Jejo
Transgene Detail

Summary

• Symbol: Tg(Ascl1-EGFP,-cre)1Jejo
• Name: transgene insertion 1, Jane Johnson
• MGI ID: MGI:3767431
• Synonyms: Ascl1-GIC, M1-GIC, Tg(RPCI-428P21-EGFP,-cre)1Jejo
• Transgene: Tg(Ascl1-EGFP,-cre)1Jejo Location: unknown
• Alliance: Tg(Ascl1-EGFP,-cre)1Jejo page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA)F1

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Ascl1-EGFP,-cre)1Jejo expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Ascl1 (MGI:96919)

• Mutation details: The transgene is a bacterial artificial chromosome (BAC), RPCI-428P2, bearing a 305 kb mouse genomic segment that contains the Ascl1 locus(98 kb of 5' and 206 kb of 3' of the start codon), in which the coding sequence of the gene has been replaced with an EGFP-IRES-CRE cassette. The GFP reporter expression is low but reflects the Ascl1 pattern throughout multiple stages and in multiple regions, including the caudal neural tube, the telencephalon and diencephalon, and sympathetic and enteric nervous systems. (J:98830, J:117032)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Ascl1 (mouse) Summary of all recombinase alleles driven by Ascl1. Comparative matrix view of recombinase activities Alliance mouse Ascl1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:98830 Helms AW, et al., Sequential roles for Mash1 and Ngn2 in the generation of dorsal spinal cord interneurons. Development. 2005 Jun;132(12):2709-19
• All: 8 reference(s)