Tg(CAG-EGFP-CAT-DTA)2Masa
Transgene Detail

Summary

• Symbol: Tg(CAG-EGFP-CAT-DTA)2Masa
• Name: transgene insertion 2, Masahiro Sato
• MGI ID: MGI:3767445
• Synonyms: CETD, CETD-2
• Transgene: Tg(CAG-EGFP-CAT-DTA)2Masa Location: unknown
• Alliance: Tg(CAG-EGFP-CAT-DTA)2Masa page

Transgene origin

• Strain of Origin: (C57BL/6 x C3H)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The chicken actin (CAG) promoter drives the expression of EGFP, CAT and diphtheria toxin-A. LoxP sites are located between the promoter and EGFP, and betwen coding regions of CAT and ditheria toxin-A. Expression of EGFP was detected in the skeletal muscle, heart, pancreas and kidney. (J:128247)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

Lines 2 and 4 were created; however, line 2 has brighter expression than line 4 and was therefore chosen as the representative line.

References

• Original: J:128247 Sato M, et al., Production of CETD transgenic mouse line allowing ablation of any type of specific cell population. Mol Reprod Dev. 2005 Sep;72(1):54-67
• All: 2 reference(s)