Celf3^tm1Ade
Targeted Allele Detail

Summary

• Symbol: Celf3^tm1Ade
• Name: CUGBP, Elav-like family member 3; targeted mutation 1, Arvind Dev
• MGI ID: MGI:3767553
• Synonyms: Brunol1^-
• Gene: Celf3 Location: Chr3:94385602-94399505 bp, + strand Genetic Position: Chr3, 40.73 cM
• Alliance: Celf3^tm1Ade page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:128362
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A pgk-neo cassette replaced exons 3 - 12 via homologous recombination. Northern blot and RT-PCR analysis of testes confirmed the absence of transcript in homozygous mice. (J:128362)

Expression

In Mice Carrying this Mutation:

10 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Celf3 Mutation: 25 strains or lines available

References

• Original: J:128362 Dev A, et al., Mice deficient for RNA-binding protein brunol1 show reduction of spermatogenesis but are fertile. Mol Reprod Dev. 2007 Nov;74(11):1456-64
• All: 1 reference(s)