Tbx15^tm1Apr
Targeted Allele Detail

Summary

• Symbol: Tbx15^tm1Apr
• Name: T-box 15; targeted mutation 1, Andreas P Russ
• MGI ID: MGI:3767607
• Synonyms: Tbx15^LacZ
• Gene: Tbx15 Location: Chr3:99147697-99261575 bp, + strand Genetic Position: Chr3, 43.03 cM
• Alliance: Tbx15^tm1Apr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:87455
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: An IRES-LacZ-neo cassette with 5' and 3' homology arms of 3.5 kb and 1.8 kb was inserted into a unique BamH1 site that lies 479 nucleotides downstream of the transcriptional initiation site in exon 3. This allele is predicted to give rise to a protein truncated after approximately 154 codons and is lacking critical residues of the T box. (J:87455)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tbx15 Mutation: 46 strains or lines available

References

• Original: J:87455 Candille SI, et al., Dorsoventral patterning of the mouse coat by tbx15. PLoS Biol. 2004 Jan;2(1):E3
• All: 1 reference(s)